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Novel Protein-Based Pneumococcal Vaccines: Assessing the Use of Distinct Protein Fragments Instead of Full-Length Proteins as Vaccine Antigens

Non-serotype-specific protein-based pneumococcal vaccines have received extensive research focus due to the limitations of polysaccharide-based vaccines. Pneumococcal proteins (PnPs), universally expressed among serotypes, may induce broader immune responses, stimulating humoral and cellular immunit...

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Detalles Bibliográficos
Autores principales: Lagousi, Theano, Basdeki, Paraskevi, Routsias, John, Spoulou, Vana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466302/
https://www.ncbi.nlm.nih.gov/pubmed/30669439
http://dx.doi.org/10.3390/vaccines7010009