A Three-Compartment Pharmacokinetic Model to Predict the Interstitial Concentration of Talaporfin Sodium in the Myocardium for Photodynamic Therapy: A Method Combining Measured Fluorescence and Analysis of the Compartmental Origin of the Fluorescence

To evaluate the effectiveness of photodynamic therapy occurring in the interstitial space of the myocardium, we estimated the interstitial concentration of talaporfin sodium in the canine myocardium by constructing a three-compartment pharmacokinetic model based on measured changes in talaporfin sod...

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Detalles Bibliográficos
Autores principales: Uno, Yuko, Ogawa, Emiyu, Aiyoshi, Eitaro, Arai, Tsunenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466385/
https://www.ncbi.nlm.nih.gov/pubmed/30583456
http://dx.doi.org/10.3390/bioengineering6010001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466385/
https://www.ncbi.nlm.nih.gov/pubmed/30583456
http://dx.doi.org/10.3390/bioengineering6010001

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