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Idiosyncrasies of thermofluorimetric aptamer binding assays

To explore thermofluorimetric analysis (TFA) in detail, we compared two related aptamers. The first, LINN2, is a DNA aptamer previously selected against EGFR recombinant protein. In this work we selected a second aptamer, KM4, against EGFR-overexpressing A549 cells. The two aptamers were derived fro...

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Detalles Bibliográficos
Autores principales: Damase, Tulsi Ram, Allen, Peter B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466456/
https://www.ncbi.nlm.nih.gov/pubmed/30764639
http://dx.doi.org/10.2144/btn-2018-0128