Dopamine D(4) Receptor-Selective Compounds Reveal Structure–Activity Relationships that Engender Agonist Efficacy

[Image: see text] The dopamine D(4) receptor (D(4)R) plays important roles in cognition, attention, and decision making. Novel D(4)R-selective ligands have promise in medication development for neuropsychiatric conditions, including Alzheimer’s disease and substance use disorders. To identify new D(...

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Detalles Bibliográficos
Autores principales: Keck, Thomas M., Free, R. Benjamin, Day, Marilyn M., Brown, Sonvia L., Maddaluna, Michele S., Fountain, Griffin, Cooper, Charles, Fallon, Brooke, Holmes, Matthew, Stang, Christopher T., Burkhardt, Russell, Bonifazi, Alessandro, Ellenberger, Michael P., Newman, Amy H., Sibley, David R., Wu, Chun, Boateng, Comfort A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466480/
https://www.ncbi.nlm.nih.gov/pubmed/30883109
http://dx.doi.org/10.1021/acs.jmedchem.9b00231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466480/
https://www.ncbi.nlm.nih.gov/pubmed/30883109
http://dx.doi.org/10.1021/acs.jmedchem.9b00231

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