Synthesis and Anti-HIV Profile of a Novel Tetrahydroindazolylbenzamide Derivative Obtained by Oxazolone Chemistry

[Image: see text] A new tetrahydroindazolylbenzamide derivative has been synthesized, characterized, and evaluated as HIV-inhibitor. The biological data revealed the ability to inhibit HIV proliferation with low cytotoxicity allowing for significant selectivity (EC(50) 2.77 μM; CC(50) 118.7 μM; SI =...

Descripción completa

Detalles Bibliográficos
Autores principales: Scala, Angela, Piperno, Anna, Micale, Nicola, Christ, Frauke, Debyser, Zeger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466547/
https://www.ncbi.nlm.nih.gov/pubmed/30996769
http://dx.doi.org/10.1021/acsmedchemlett.8b00511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466547/
https://www.ncbi.nlm.nih.gov/pubmed/30996769
http://dx.doi.org/10.1021/acsmedchemlett.8b00511

Ejemplares similares