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CRISPR-Cas: Converting A Bacterial Defence Mechanism into A State-of-the-Art Genetic Manipulation Tool

Bacteriophages are pervasive viruses that infect bacteria, relying on their genetic machinery to replicate. In order to protect themselves from this kind of invader, bacteria developed an ingenious adaptive defence system, clustered regularly interspaced short palindromic repeats (CRISPR). Researche...

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Detalles Bibliográficos
Autores principales: Loureiro, Alexandre, da Silva, Gabriela Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466564/
https://www.ncbi.nlm.nih.gov/pubmed/30823430
http://dx.doi.org/10.3390/antibiotics8010018