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A Molecular Modeling Approach to Identify Novel Inhibitors of the Major Facilitator Superfamily of Efflux Pump Transporters

Multidrug efflux systems play a prominent role in medicine, as they are important contributors to bacterial antibiotic resistance. NorA is an efflux pump transporter from the major facilitator superfamily that expels numerous drug compounds across the inner membrane of Staphylococcus aureus (S. aure...

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Detalles Bibliográficos
Autores principales: Zárate, Sandra G., Morales, Paula, Świderek, Katarzyna, Bolanos-Garcia, Victor M., Bastida, Agatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466568/
https://www.ncbi.nlm.nih.gov/pubmed/30875968
http://dx.doi.org/10.3390/antibiotics8010025