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A Molecular Modeling Approach to Identify Novel Inhibitors of the Major Facilitator Superfamily of Efflux Pump Transporters
Multidrug efflux systems play a prominent role in medicine, as they are important contributors to bacterial antibiotic resistance. NorA is an efflux pump transporter from the major facilitator superfamily that expels numerous drug compounds across the inner membrane of Staphylococcus aureus (S. aure...
Autores principales: | Zárate, Sandra G., Morales, Paula, Świderek, Katarzyna, Bolanos-Garcia, Victor M., Bastida, Agatha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466568/ https://www.ncbi.nlm.nih.gov/pubmed/30875968 http://dx.doi.org/10.3390/antibiotics8010025 |
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