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Non-Mammalian Prdx6 Enzymes (Proteins with 1-Cys Prdx Mechanism) Display PLA(2) Activity Similar to the Human Orthologue

Mammalian peroxiredoxin class 6 (Prdx6) are bifunctional enzymes. Non-mammalian Prdx6 enzymes display Cys-based peroxidase activity, but to date their putative phospholipase A(2) (PLA(2) activities) has not been experimentally investigated. Initially, we observed that five non-mammalian Prdx6 enzyme...

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Detalles Bibliográficos
Autores principales: Bannitz-Fernandes, Renata, Aleixo-Silva, Rogério, Silva, João Paulo, Dodia, Chandra, Vazquez-Medina, Jose Pablo, Tao, Jian-Qin, Fisher, Aron, Netto, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466579/
https://www.ncbi.nlm.nih.gov/pubmed/30832204
http://dx.doi.org/10.3390/antiox8030052