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IFITM3 directly engages and shuttles incoming virus particles to lysosomes

Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) have emerged as important innate immune effectors that prevent diverse virus infections in vertebrates. However, the cellular mechanisms and live-cell imaging of these small membrane proteins have been challenging to evaluate during viral...

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Detalles Bibliográficos
Autores principales: Spence, Jennifer S., He, Ruina, Hoffmann, Hans-Heinrich, Das, Tandrila, Thinon, Emmanuelle, Rice, Charles M., Peng, Tao, Chandran, Kartik, Hang, Howard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466627/
https://www.ncbi.nlm.nih.gov/pubmed/30643282
http://dx.doi.org/10.1038/s41589-018-0213-2