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IFITM3 directly engages and shuttles incoming virus particles to lysosomes
Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) have emerged as important innate immune effectors that prevent diverse virus infections in vertebrates. However, the cellular mechanisms and live-cell imaging of these small membrane proteins have been challenging to evaluate during viral...
Autores principales: | Spence, Jennifer S., He, Ruina, Hoffmann, Hans-Heinrich, Das, Tandrila, Thinon, Emmanuelle, Rice, Charles M., Peng, Tao, Chandran, Kartik, Hang, Howard C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466627/ https://www.ncbi.nlm.nih.gov/pubmed/30643282 http://dx.doi.org/10.1038/s41589-018-0213-2 |
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