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The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning
BACKGROUND: Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures. However, its precise mechanism remains elusive. In this report, we describe roles of the NuA4 acetyltransferase and histone H4 acetylat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466672/ https://www.ncbi.nlm.nih.gov/pubmed/30992049 http://dx.doi.org/10.1186/s13072-019-0271-z |