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The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning

BACKGROUND: Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures. However, its precise mechanism remains elusive. In this report, we describe roles of the NuA4 acetyltransferase and histone H4 acetylat...

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Detalles Bibliográficos
Autores principales: Noguchi, Chiaki, Singh, Tanu, Ziegler, Melissa A., Peake, Jasmine D., Khair, Lyne, Aza, Ana, Nakamura, Toru M., Noguchi, Eishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466672/
https://www.ncbi.nlm.nih.gov/pubmed/30992049
http://dx.doi.org/10.1186/s13072-019-0271-z