Abnormal level of CUL4B-mediated histone H2A ubiquitination causes disruptive HOX gene expression

BACKGROUND: Neural tube defects (NTDs) are common birth defects involving the central nervous system. Recent studies on the etiology of human NTDs have raised the possibility that epigenetic regulation could be involved in determining susceptibility to them. RESULTS: Here, we show that the H2AK119ub...

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Detalles Bibliográficos
Autores principales: Lin, Ye, Yu, Juan, Wu, Jianxin, Wang, Shan, Zhang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466687/
https://www.ncbi.nlm.nih.gov/pubmed/30992047
http://dx.doi.org/10.1186/s13072-019-0268-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466687/
https://www.ncbi.nlm.nih.gov/pubmed/30992047
http://dx.doi.org/10.1186/s13072-019-0268-7

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