Tat inhibition by didehydro-Cortistatin A promotes heterochromatin formation at the HIV-1 long terminal repeat

BACKGROUND: Transcription from the integrated HIV-1 promoter is directly governed by its chromatin environment, and the nucleosome-1 downstream from the transcription start site directly impedes transcription from the HIV-1 promoter. The HIV-1 Tat protein regulates the passage from viral latency to...

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Detalles Bibliográficos
Autores principales: Li, Chuan, Mousseau, Guillaume, Valente, Susana T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466689/
https://www.ncbi.nlm.nih.gov/pubmed/30992052
http://dx.doi.org/10.1186/s13072-019-0267-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466689/
https://www.ncbi.nlm.nih.gov/pubmed/30992052
http://dx.doi.org/10.1186/s13072-019-0267-8

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