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Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways

BACKGROUND: Currently offered therapeutics to treat colon cancer (CoCa) are toxic when given at maximum tolerated dose to achieve optimal clinical response. Hence, less toxic therapeutic intervention is needed to treat CoCa. In this study, we investigated the effect of a natural agent, Emodin, on Co...

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Detalles Bibliográficos
Autores principales: Saunders, Ian T., Mir, Hina, Kapur, Neeraj, Singh, Shailesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466701/
https://www.ncbi.nlm.nih.gov/pubmed/31011292
http://dx.doi.org/10.1186/s12935-019-0820-3