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Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27
BACKGROUND: Adult stem cells exist in a quiescent state (G0) within the in vivo niche; the loss of quiescence often leads to a decrease in the number and function of adult stem cells, impairing tissue regeneration and repair. Endogenous repair by nucleus pulposus-derived stem cells has recently show...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466800/ https://www.ncbi.nlm.nih.gov/pubmed/30987681 http://dx.doi.org/10.1186/s13287-019-1219-8 |