Siah2 modulates sex-dependent metabolic and inflammatory responses in adipose tissue to a high-fat diet challenge

BACKGROUND: The obesity-related risk of developing metabolic syndrome is higher in males than in females of reproductive age, likely due to estrogen-mediated reduced adipose tissue inflammation and fibrosis with hypertrophied adipocytes. Depletion of the ubiquitin ligase Siah2 reduced white adipose...

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Detalles Bibliográficos
Autores principales: Ghosh, Sujoy, Taylor, Jessica L., Mendoza, Tamra M., Dang, Thanh, Burk, David H., Yu, Yongmei, Kilroy, Gail, Floyd, Z. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466809/
https://www.ncbi.nlm.nih.gov/pubmed/30987673
http://dx.doi.org/10.1186/s13293-019-0233-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466809/
https://www.ncbi.nlm.nih.gov/pubmed/30987673
http://dx.doi.org/10.1186/s13293-019-0233-y

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