Behind the Mirror: Chirality Tunes the Reactivity and Cytotoxicity of Chloropiperidines as Potential Anticancer Agents

[Image: see text] The pressing demand for sustainable antitumor drugs prompted us to investigate 3-chloropiperidines as potential mustard-based anticancer agents. In this study, an explorative set of variously decorated monofunctional 3-chloropiperidines (M-CePs) was efficiently synthesized through...

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Detalles Bibliográficos
Autores principales: Carraro, Caterina, Francke, Alexander, Sosic, Alice, Kohl, Franziska, Helbing, Tim, De Franco, Michele, Fabris, Daniele, Göttlich, Richard, Gatto, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466835/
https://www.ncbi.nlm.nih.gov/pubmed/30996795
http://dx.doi.org/10.1021/acsmedchemlett.8b00580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466835/
https://www.ncbi.nlm.nih.gov/pubmed/30996795
http://dx.doi.org/10.1021/acsmedchemlett.8b00580

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