A RADAR-Based Assay to Isolate Covalent DNA Complexes in Bacteria

Quinolone antibacterials target the type II topoisomerases gyrase and topoisomerase IV and kill bacterial cells by converting these essential enzymes into cellular poisons. Although much is known regarding the interactions between these drugs and enzymes in purified systems, much less is known regar...

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Detalles Bibliográficos
Autores principales: Aldred, Katie J., Payne, Adeline, Voegerl, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466838/
https://www.ncbi.nlm.nih.gov/pubmed/30818799
http://dx.doi.org/10.3390/antibiotics8010017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466838/
https://www.ncbi.nlm.nih.gov/pubmed/30818799
http://dx.doi.org/10.3390/antibiotics8010017

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