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The Mycobacterium tuberculosis CRISPR-Associated Cas1 Involves Persistence and Tolerance to Anti-Tubercular Drugs

Tuberculosis remains one of the leading causes of death worldwide. Even if new antitubercular drugs are currently being developed, the rapid emergence and spread of drug-resistant strain remain a severe challenge. The CRISPR associated proteins 1 (Cas1), a most conserved endonuclease which is respon...

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Detalles Bibliográficos
Autores principales: Wei, Jiawei, Lu, Nan, Li, Zhiying, Wu, Xuanyan, Jiang, Tao, Xu, Li, Yang, Chun, Guo, Shuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466960/
https://www.ncbi.nlm.nih.gov/pubmed/31061828
http://dx.doi.org/10.1155/2019/7861695