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Aberrant DNA Methylation of Two Tumor Suppressor Genes, p14(ARF) and p15(INK4b), after Chronic Occupational Exposure to Low Level of Benzene

BACKGROUND: Exposure to benzene would be associated with many diseases including leukemia. Epigenetic alterations seem to be among the main mechanisms involved. OBJECTIVE: To determine if chronic occupational exposure to low level of benzene would be associated with DNA methylation. METHODS: Global...

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Detalles Bibliográficos
Autores principales: Jamebozorgi, Iraj, Majidizadeh, Tayebeh, Pouryaghoub, Gholamreza, Mahjoubi, Frouzandeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz: NIOC Health Organization 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466977/
https://www.ncbi.nlm.nih.gov/pubmed/29995020
http://dx.doi.org/10.15171/ijoem.2018.1317