Oncogenic splicing factor SRSF3 regulates ILF3 alternative splicing to promote cancer cell proliferation and transformation

Alternative RNA splicing is an important focus in molecular and clinical oncology. We report here that SRSF3 regulates alternative RNA splicing of interleukin enhancer binding factor 3 (ILF3) and production of this double-strand RNA-binding protein. An increased coexpression of ILF3 isoforms and SRS...

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Detalles Bibliográficos
Autores principales: Jia, Rong, Ajiro, Masahiko, Yu, Lulu, McCoy, Philip, Zheng, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467003/
https://www.ncbi.nlm.nih.gov/pubmed/30796096
http://dx.doi.org/10.1261/rna.068619.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467003/
https://www.ncbi.nlm.nih.gov/pubmed/30796096
http://dx.doi.org/10.1261/rna.068619.118

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