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Programmable RNA detection with a fluorescent RNA aptamer using optimized three-way junction formation

RNAs play essential roles in various cellular processes and can be used as biomarkers. Hence, it is important to detect endogenous RNA for understanding diverse cellular functions and diagnosing diseases. To construct a low-cost and easy-to-use RNA detection probe, a chemically unmodified RNA aptame...

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Detalles Bibliográficos
Autores principales: Furuhata, Yuichi, Kobayashi, Mizuki, Maruyama, Ryo, Sato, Yusuke, Makino, Kurumi, Michiue, Tatsuo, Yui, Hiroharu, Nishizawa, Seiichi, Yoshimoto, Keitaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467008/
https://www.ncbi.nlm.nih.gov/pubmed/30745364
http://dx.doi.org/10.1261/rna.069062.118