Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial

Rationale: There remains uncertainty about the role of corticosteroids in sepsis with clear beneficial effects on shock duration, but conflicting survival effects. Two transcriptomic sepsis response signatures (SRSs) have been identified. SRS1 is relatively immunosuppressed, whereas SRS2 is relative...

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Detalles Bibliográficos
Autores principales: Antcliffe, David B., Burnham, Katie L., Al-Beidh, Farah, Santhakumaran, Shalini, Brett, Stephen J., Hinds, Charles J., Ashby, Deborah, Knight, Julian C., Gordon, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467319/
https://www.ncbi.nlm.nih.gov/pubmed/30365341
http://dx.doi.org/10.1164/rccm.201807-1419OC

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467319/
https://www.ncbi.nlm.nih.gov/pubmed/30365341
http://dx.doi.org/10.1164/rccm.201807-1419OC

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