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IL-1A gene variation in relation to cytokine levels and clinical characteristics in ankylosing spondylitis

OBJECTIVE: Variations in the IL-1 alpha (IL-A) gene increase the risk for ankylosing spondylitis (AS), but the pathway underlying this association is not fully understood. As IL-1A is primarily a regulatory cytokine, we investigated the influence of IL-1A gene variation on disease severity and cytok...

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Detalles Bibliográficos
Autores principales: Nossent, Johannes C., Sagen-Johnsen, Sylvia, Bakland, Gunnstein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical Research and Education Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467326/
https://www.ncbi.nlm.nih.gov/pubmed/31365338
http://dx.doi.org/10.5152/eurjrheum.2018.18150