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Ruxolitinib: a targeted treatment option for patients with polycythemia vera

Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by erythrocytosis and the presence of Janus kinase (JAK) 2V617F or similar mutations. This review summarizes the pathophysiology of PV, the challenges associated with traditional treatment options, and the scientific ratio...

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Detalles Bibliográficos
Autores principales: Vaddi, Kris, Verstovsek, Srdan, Kiladjian, Jean-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467337/
https://www.ncbi.nlm.nih.gov/pubmed/31360077
http://dx.doi.org/10.2147/BLCTT.S101185