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Ruxolitinib: a targeted treatment option for patients with polycythemia vera
Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by erythrocytosis and the presence of Janus kinase (JAK) 2V617F or similar mutations. This review summarizes the pathophysiology of PV, the challenges associated with traditional treatment options, and the scientific ratio...
Autores principales: | Vaddi, Kris, Verstovsek, Srdan, Kiladjian, Jean-Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467337/ https://www.ncbi.nlm.nih.gov/pubmed/31360077 http://dx.doi.org/10.2147/BLCTT.S101185 |
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