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Comparative In Vitro Toxicity Study of Docetaxel and Nanoxel, a Docetaxel-Loaded Micellar Formulation Using Cultured and Blood Cells

Nanoxel-PM(TM) (Nanoxel) is a docetaxel-loaded methoxy-poly(ethylene glycol)-block-poly(D,L-lactide) (mPEG-PDLLA). This newly developed and marketed nanoformulation exhibits an improved pharmacokinetic profile, efficacy, and safety. Although the safety of Nanoxel to docetaxel as well as its bioequiv...

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Detalles Bibliográficos
Autores principales: Do, Van Quan, Park, Kwang-Hoon, Park, Jung-Min, Lee, Moo-Yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467357/
https://www.ncbi.nlm.nih.gov/pubmed/31015902
http://dx.doi.org/10.5487/TR.2019.35.2.201