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Genetic mutational status of genes regulating epigenetics: Role of the histone methyltransferase KMT2D in triple negative breast tumors

PURPOSE: Epigenetic regulating proteins like histone methyltransferases produce variations in several functions, some of them associated with the generation of oncogenic processes. Mutations of genes involved in these functions have been recently associated with cancer, and strategies to modulate th...

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Detalles Bibliográficos
Autores principales: Morcillo-Garcia, Sara, Noblejas-Lopez, Maria del Mar, Nieto-Jimenez, Cristina, Perez-Peña, Javier, Nuncia-Cantarero, Miriam, Győrffy, Balázs, Amir, Eitan, Pandiella, Atanasio, Galan-Moya, Eva M., Ocana, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467442/
https://www.ncbi.nlm.nih.gov/pubmed/30990809
http://dx.doi.org/10.1371/journal.pone.0209134