Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern

Models based in differential expansion of elastic material, axonal constraints, directed growth, or multi-phasic combinations have been proposed to explain brain folding. However, the cellular and physical processes present during folding have not been defined. We used the murine cerebellum to chall...

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Detalles Bibliográficos
Autores principales: Lawton, Andrew K, Engstrom, Tyler, Rohrbach, Daniel, Omura, Masaaki, Turnbull, Daniel H, Mamou, Jonathan, Zhang, Teng, Schwarz, J M, Joyner, Alexandra L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467563/
https://www.ncbi.nlm.nih.gov/pubmed/30990415
http://dx.doi.org/10.7554/eLife.45019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467563/
https://www.ncbi.nlm.nih.gov/pubmed/30990415
http://dx.doi.org/10.7554/eLife.45019

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