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Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern
Models based in differential expansion of elastic material, axonal constraints, directed growth, or multi-phasic combinations have been proposed to explain brain folding. However, the cellular and physical processes present during folding have not been defined. We used the murine cerebellum to chall...
Autores principales: | Lawton, Andrew K, Engstrom, Tyler, Rohrbach, Daniel, Omura, Masaaki, Turnbull, Daniel H, Mamou, Jonathan, Zhang, Teng, Schwarz, J M, Joyner, Alexandra L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467563/ https://www.ncbi.nlm.nih.gov/pubmed/30990415 http://dx.doi.org/10.7554/eLife.45019 |
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