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Metagenomic engineering of the mammalian gut microbiome in situ
Engineering microbial communities in open environments remains challenging. Here, we describe a platform to identify and modify genetically tractable mammalian microbiota by engineering community-wide horizontal gene transfer events in situ. With this approach, we demonstrate that diverse taxa in th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467691/ https://www.ncbi.nlm.nih.gov/pubmed/30643213 http://dx.doi.org/10.1038/s41592-018-0301-y |