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Metagenomic engineering of the mammalian gut microbiome in situ

Engineering microbial communities in open environments remains challenging. Here, we describe a platform to identify and modify genetically tractable mammalian microbiota by engineering community-wide horizontal gene transfer events in situ. With this approach, we demonstrate that diverse taxa in th...

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Detalles Bibliográficos
Autores principales: Ronda, Carlotta, Chen, Sway P., Cabral, Vitor, Yaung, Stephanie J., Wang, Harris H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467691/
https://www.ncbi.nlm.nih.gov/pubmed/30643213
http://dx.doi.org/10.1038/s41592-018-0301-y