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A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable Effects

BACKGROUND: Deep brain stimulation (DBS) is an emerging treatment for severe obsessive-compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal (VC/VS) and anteromedial subthalamic nucleus (amSTN) DBS in the same patients and tested for mechanistic differences on mood...

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Detalles Bibliográficos
Autores principales: Tyagi, Himanshu, Apergis-Schoute, Annemieke M., Akram, Harith, Foltynie, Tom, Limousin, Patricia, Drummond, Lynne M., Fineberg, Naomi A., Matthews, Keith, Jahanshahi, Marjan, Robbins, Trevor W., Sahakian, Barbara J., Zrinzo, Ludvic, Hariz, Marwan, Joyce, Eileen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467837/
https://www.ncbi.nlm.nih.gov/pubmed/30853111
http://dx.doi.org/10.1016/j.biopsych.2019.01.017