A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division

Leishmaniasis is a neglected disease that affects more than 12 million people, with a limited therapy. Plant-derived natural products represent a useful source of anti-protozoan prototypes. In this work, four derivatives were prepared from neolignans isolated from the Brazilian plant Nectandra leuca...

Descripción completa

Detalles Bibliográficos
Autores principales: Amaral, Maiara, de Sousa, Fernanda S., Silva, Thais A. Costa, Junior, Andrés Jimenez G., Taniwaki, Noemi N., Johns, Deidre M., Lago, João Henrique G., Anderson, Edward A., Tempone, Andre G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467890/
https://www.ncbi.nlm.nih.gov/pubmed/30992481
http://dx.doi.org/10.1038/s41598-019-42273-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467890/
https://www.ncbi.nlm.nih.gov/pubmed/30992481
http://dx.doi.org/10.1038/s41598-019-42273-z

Ejemplares similares