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Designed Mutations Alter the Binding Pathways of an Intrinsically Disordered Protein
Many cellular functions, including signaling and regulation, are carried out by intrinsically disordered proteins (IDPs) binding to their targets. Experimental and computational studies have now significantly advanced our understanding of these binding processes. In particular, IDPs that become stru...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467919/ https://www.ncbi.nlm.nih.gov/pubmed/30992509 http://dx.doi.org/10.1038/s41598-019-42717-6 |