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Designed Mutations Alter the Binding Pathways of an Intrinsically Disordered Protein

Many cellular functions, including signaling and regulation, are carried out by intrinsically disordered proteins (IDPs) binding to their targets. Experimental and computational studies have now significantly advanced our understanding of these binding processes. In particular, IDPs that become stru...

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Detalles Bibliográficos
Autores principales: Wu, Di, Zhou, Huan-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467919/
https://www.ncbi.nlm.nih.gov/pubmed/30992509
http://dx.doi.org/10.1038/s41598-019-42717-6