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A Novel Antibody-Toxin Conjugate to Treat Mantle Cell Lymphoma
Matriptase is a transmembrane serine protease, synthesized as an inactive single-chain zymogen on the endoplasmic reticulum and transported to the plasma membrane. Matriptase is activated in different epithelial and some B-cell malignancies and changes its conformation and activity is inhibited main...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467949/ https://www.ncbi.nlm.nih.gov/pubmed/31024856 http://dx.doi.org/10.3389/fonc.2019.00258 |