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A Novel Antibody-Toxin Conjugate to Treat Mantle Cell Lymphoma

Matriptase is a transmembrane serine protease, synthesized as an inactive single-chain zymogen on the endoplasmic reticulum and transported to the plasma membrane. Matriptase is activated in different epithelial and some B-cell malignancies and changes its conformation and activity is inhibited main...

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Detalles Bibliográficos
Autores principales:	Rather, Gulam M., Lin, Siang-Yo, Lin, Hongxia, Szekely, Zoltan, Bertino, Joseph R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467949/ https://www.ncbi.nlm.nih.gov/pubmed/31024856 http://dx.doi.org/10.3389/fonc.2019.00258

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