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Inhibitory Effect of KP-A038 on Osteoclastogenesis and Inflammatory Bone Loss Is Associated With Downregulation of Blimp1

Excessive osteoclastic activity results in pathological bone resorptive diseases, such as osteoporosis, periodontitis, and rheumatoid arthritis. As imidazole-containing compounds possess extensive therapeutic potential for the management of diverse diseases, we synthesized a series of imidazole deri...

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Detalles Bibliográficos
Autores principales: Ihn, Hye Jung, Lee, Taeho, Lee, Doohyun, Bae, Jong-Sup, Kim, Sang-Hyun, Jang, Il Ho, Bae, Yong Chul, Shin, Hong-In, Park, Eui Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467953/
https://www.ncbi.nlm.nih.gov/pubmed/31024321
http://dx.doi.org/10.3389/fphar.2019.00367