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Inhibitory Effect of KP-A038 on Osteoclastogenesis and Inflammatory Bone Loss Is Associated With Downregulation of Blimp1
Excessive osteoclastic activity results in pathological bone resorptive diseases, such as osteoporosis, periodontitis, and rheumatoid arthritis. As imidazole-containing compounds possess extensive therapeutic potential for the management of diverse diseases, we synthesized a series of imidazole deri...
Autores principales: | Ihn, Hye Jung, Lee, Taeho, Lee, Doohyun, Bae, Jong-Sup, Kim, Sang-Hyun, Jang, Il Ho, Bae, Yong Chul, Shin, Hong-In, Park, Eui Kyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467953/ https://www.ncbi.nlm.nih.gov/pubmed/31024321 http://dx.doi.org/10.3389/fphar.2019.00367 |
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