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Comparing Hydrolysis and Transglycosylation Reactions Catalyzed by Thermus thermophilus β-Glycosidase. A Combined MD and QM/MM Study

The synthesis of oligosaccharides and other carbohydrate derivatives is of relevance for the advancement of glycosciences both at the fundamental and applied level. For many years, glycosyl hydrolases (GHs) have been explored to catalyze the synthesis of glycosidic bonds. In particular, retaining GH...

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Detalles Bibliográficos
Autores principales: Romero-Téllez, Sonia, Lluch, José M., González-Lafont, Àngels, Masgrau, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467970/
https://www.ncbi.nlm.nih.gov/pubmed/31024890
http://dx.doi.org/10.3389/fchem.2019.00200