RNA recognition motifs of disease-linked RNA-binding proteins contribute to amyloid formation

Aberrant expression, dysfunction and particularly aggregation of a group of RNA-binding proteins, including TDP-43, FUS and RBM45, are associated with neurological disorders. These three disease-linked RNA-binding proteins all contain at least one RNA recognition motif (RRM). However, it is not clea...

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Detalles Bibliográficos
Autores principales: Agrawal, Sashank, Kuo, Pan-Hsien, Chu, Lee-Ya, Golzarroshan, Bagher, Jain, Monika, Yuan, Hanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467989/
https://www.ncbi.nlm.nih.gov/pubmed/30992467
http://dx.doi.org/10.1038/s41598-019-42367-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467989/
https://www.ncbi.nlm.nih.gov/pubmed/30992467
http://dx.doi.org/10.1038/s41598-019-42367-8

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