Maf deficiency in T cells dysregulates T(reg) - T(H)17 balance leading to spontaneous colitis

The maintenance of homeostasis in the gut is a major challenge for the immune system. Here we demonstrate that the transcription factor MAF plays a central role in T cells for the prevention of gastro-intestinal inflammation. Conditional knock out mice lacking Maf in all T cells developed spontaneou...

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Detalles Bibliográficos
Autores principales: Imbratta, Claire, Leblond, Marine M., Bouzourène, Hanifa, Speiser, Daniel E., Velin, Dominique, Verdeil, Grégory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468010/
https://www.ncbi.nlm.nih.gov/pubmed/30992496
http://dx.doi.org/10.1038/s41598-019-42486-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468010/
https://www.ncbi.nlm.nih.gov/pubmed/30992496
http://dx.doi.org/10.1038/s41598-019-42486-2

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