Dgcr8 deletion in the primitive heart uncovered novel microRNA regulating the balance of cardiac-vascular gene program

Primitive mammalian heart transforms from a single tube to a four-chambered muscular organ during a short developmental window. We found that knocking out global microRNA by deleting Dgcr8 microprocessor in Mesp1 cardiovascular progenitor cells lead to the formation of extremely dilated and enlarged...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xi, Wang, Lin, Huang, Rujin, Qiu, Hui, Wang, Peizhe, Wu, Daren, Zhu, Yonglin, Ming, Jia, Wang, Yangming, Wang, Jianbin, Na, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468043/
https://www.ncbi.nlm.nih.gov/pubmed/30128894
http://dx.doi.org/10.1007/s13238-018-0572-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468043/
https://www.ncbi.nlm.nih.gov/pubmed/30128894
http://dx.doi.org/10.1007/s13238-018-0572-1

Ejemplares similares