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Dgcr8 deletion in the primitive heart uncovered novel microRNA regulating the balance of cardiac-vascular gene program

Primitive mammalian heart transforms from a single tube to a four-chambered muscular organ during a short developmental window. We found that knocking out global microRNA by deleting Dgcr8 microprocessor in Mesp1 cardiovascular progenitor cells lead to the formation of extremely dilated and enlarged...

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Detalles Bibliográficos
Autores principales:	Chen, Xi, Wang, Lin, Huang, Rujin, Qiu, Hui, Wang, Peizhe, Wu, Daren, Zhu, Yonglin, Ming, Jia, Wang, Yangming, Wang, Jianbin, Na, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468043/ https://www.ncbi.nlm.nih.gov/pubmed/30128894 http://dx.doi.org/10.1007/s13238-018-0572-1

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