In Silico Exploration of Aryl Halides Analogues as Checkpoint Kinase 1 Inhibitors by Using 3D QSAR, Molecular Docking Study, and ADMET Screening

Purpose: In this review, a set of aryl halides analogs were identified as potent checkpoint kinase 1 (Chk1) inhibitors through a series of computer-aided drug design processes, to develop models with good predictive ability, highlight the important interactions between the ligand and the Chk1 recept...

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Detalles Bibliográficos
Autores principales: Ghaleb, Adib, Aouidate, Adnane, Bouachrine, Mohammed, Lakhlifi, Tahar, Sbai, Abdelouhid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468235/
https://www.ncbi.nlm.nih.gov/pubmed/31011562
http://dx.doi.org/10.15171/apb.2019.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468235/
https://www.ncbi.nlm.nih.gov/pubmed/31011562
http://dx.doi.org/10.15171/apb.2019.011

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