CRISPR-assisted multi-dimensional regulation for fine-tuning gene expression in Bacillus subtilis

Fine-tuning of gene expression is crucial for protein expression and pathway construction, but it still faces formidable challenges due to the hierarchical gene regulation at multiple levels in a context-dependent manner. In this study, we defined the optimal targeting windows for CRISPRa and CRISPR...

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Detalles Bibliográficos
Autores principales: Lu, Zhenghui, Yang, Shihui, Yuan, Xin, Shi, Yunyun, Ouyang, Li, Jiang, Sijing, Yi, Li, Zhang, Guimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468239/
https://www.ncbi.nlm.nih.gov/pubmed/30767015
http://dx.doi.org/10.1093/nar/gkz072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468239/
https://www.ncbi.nlm.nih.gov/pubmed/30767015
http://dx.doi.org/10.1093/nar/gkz072

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