Cargando…
Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB
Newly synthesized mitochondrial RNA is concentrated in structures juxtaposed to nucleoids, called RNA granules, that have been implicated in mitochondrial RNA processing and ribosome biogenesis. Here we show that two classical mtDNA replication factors, the mtDNA helicase Twinkle and single-stranded...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468249/ https://www.ncbi.nlm.nih.gov/pubmed/30715486 http://dx.doi.org/10.1093/nar/gkz047 |