Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB

Newly synthesized mitochondrial RNA is concentrated in structures juxtaposed to nucleoids, called RNA granules, that have been implicated in mitochondrial RNA processing and ribosome biogenesis. Here we show that two classical mtDNA replication factors, the mtDNA helicase Twinkle and single-stranded...

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Detalles Bibliográficos
Autores principales: Hensen, Fenna, Potter, Alisa, van Esveld, Selma L, Tarrés-Solé, Aleix, Chakraborty, Arka, Solà, Maria, Spelbrink, Johannes N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468249/
https://www.ncbi.nlm.nih.gov/pubmed/30715486
http://dx.doi.org/10.1093/nar/gkz047

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