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Recognition of ASF1 by Using Hydrocarbon‐Constrained Peptides

Inhibiting the histone H3–ASF1 (anti‐silencing function 1) protein–protein interaction (PPI) represents a potential approach for treating numerous cancers. As an α‐helix‐mediated PPI, constraining the key histone H3 helix (residues 118–135) is a strategy through which chemical probes might be elabor...

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Detalles Bibliográficos
Autores principales: Bakail, May, Rodriguez‐Marin, Silvia, Hegedüs, Zsófia, Perrin, Marie E., Ochsenbein, Françoise, Wilson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468270/
https://www.ncbi.nlm.nih.gov/pubmed/30512234
http://dx.doi.org/10.1002/cbic.201800633